365DisInFx™ UVA disinfection technology was tested using in-vitro methods as described in detail in Citations 1 & 2 below (Livingston, Kvam) which resulted in 99.7% reduction in MRSA on surfaces exposed to 3W/m2 of 365nm UVA over a single 8-hour period. Results of this testing demonstrated significant reduction over a similar exposure period of certain common pathogens including MRSA, Staphylococcus aureus, Enterococcus faecalis, Escherichia coli, Acinetobacter baumannii, Pseudomonas aeruginosa, Candida albicans and auris, associated with Hospital Acquired Infections (HAIs). Photobiological science and mathematical modeling enables us to calculate expected inactivation rates for 24-hour continuous operation of the 365DisInFx™ UVA technology.
Notes & Citations:
1 Livingston SH, Cadnum JL, Benner KJ, Donskey CJ (2020) Efficacy of an ultraviolet-A lighting system for continuous decontamination of health care-associated pathogens on surfaces. Am. J. Infect. Control 48: 337-339. https://doi.org/10.1016/j.ajic.2019.08.003
- Inoculated steel disk carriers, modification of ASTM E-2197-02
- Using a benchtop device that delivered the 3W/m² irradiance.
2 Kvam E, Benner K (2017) Disinfection via LED Lighting: summary of mechanism and results for 365nm-mediated inactivation of microbes. GE Global Research Technical Information Series 2017GRC0545, GE Confidential (Class 3)
Kvam E, Benner K. Mechanistic insights into UV-A mediated bacterial disinfection via endogenous photosensitizers. Journal of Photochemistry and Photobiology B: Biology. 2020;209:111899. doi:10.1016/j.jphotobiol.2020.111899.
- Aqueous cultures were diluted in sterile water and dried onto hydrophilic glass slides.
- Using a benchtop device that delivered the 3W/m² irradiance.
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